主要规格及技术指标

The MultiClamp™ 700B Microelectrode Amplifier is a versatile, computer-controlled microelectrode amplifier designed for patch voltage-clamp (resistive-feedback, four ranges) or high-speed current clamp (voltage-follower, three ranges) recording within the same headstage. Many automated functions and effective signal conditioning. Ideal for many applications, including high-speed current clamp (sharp-electrode or field potentials), patch clamp (whole-cell, macro-patch, or excised patch), voltammetry/amperometry, ion-selective measurements and bilayer recordings. Add two more optional headstage (voltage-follower) inputs for a four-point recording system, ideal for complex synaptic recordings. Major new features of the MultiClamp 700B Amplifier include Internal Automatic Mode switching, triggered by external signals or the recording itself; Oscillation Suppression for better cell protection; and Slow Current Injection to compensate for drifting potentials. MultiClamp 700B微电极放大器是一种多功能的、计算机控制的微电极放大器，设计用于膜片电压钳(电阻反馈，四个量程)或高速电流钳(电压跟随，三个量程)记录在同一个探头。拥有许多自动化功能和有效的信号调理。适合许多应用，包括高速电流钳(尖锐电极或场电位)，膜片钳(全细胞，大贴片，或切除贴片)，伏安/安培法，离子选择测量和双层记录。为一个四点记录系统增加两个可选的头级(电压跟随器)输入，非常适合复杂的突触记录。多钳700B放大器的主要新功能包括内部自动模式切换，由外部信号或录音本身触发;振荡抑制更好的电池保护;和慢电流注入，以补偿漂移电位。

主要功能及特色

Support of up to four headstages makes the MultiClamp 700B System four amplifiers in one.
Software control of all amplifier settings for automated optimization features, reduction of manipulation steps, and convenient, reliable telegraphing.
Quick Select Feature recalls up to three saved amplifier configurations for fast, reproducible application switching.
Optional SoftPanel allows amplifier control using knobs and buttons for a more conventional feel to amplifier control.
Integrated seal test in voltage- and current-clamp mode for easy monitoring of membrane and cell health parameters.
Dual Command Potentials add flexibility by processing input signals from two different sources.
Selectable command sensitivity for flexible control of the output waveform.
Pipette offset compensation with auto-mode quickly removes signal offsets.
Automatic pipette capacitance compensation requires only the push of a button to neutralize the contribution of the glass pipette and the pipette holder to the capacitance of the circuitry.
Series resistance compensation: Prediction helps achieve the desired command level faster by transiently supercharging the membrane potential.
Series resistance compensation: Correction improves the bandwidth of the recording by eliminating the error introduced by the voltage drop across the series resistance.
Automatic cell capacitance compensation corrects for the capacitance of the cell membrane in whole-cell recordings with a single mouse click.
Automatic mode switching enables you to control the transition between voltage and current clamp by an external trigger or depending on the recorded signal.
Automatic oscillation detection prevents damage to a cell when electrical feedback occurs.
Leak subtraction for automatic correction of leak currents with a smart, software-based algorithm.
Selectable output gain with 11 settings to scale the output signal to the desired level.
Audio monitor for acoustic tracking of the signal while you are busy looking down a microscope.
Fine-tunable 4-pole bessel and butterworth low-pass filters act as anti-aliasing filters and can be used to pre-condition the output signal. 最多支持四个探头，使 MultiClamp 700B 系统将四个放大器合二为一。
软件控制所有放大器设置以实现自动优化功能、减少操作步骤和方便、可靠的电报。
快速选择功能最多可调用三个已保存的放大器配置，以实现快速、可重复的应用切换。
可选的 SoftPanel 允许使用旋钮和按钮进行放大器控制，以获得更传统的放大器控制感觉。
电压钳和电流钳模式下的集成密封测试，可轻松监测膜和细胞健康参数。
双命令电位通过处理来自两个不同来源的输入信号来增加灵活性。
可选择命令灵敏度，灵活控制输出波形。
带有自动模式的移液器偏移补偿可快速消除信号偏移。
自动移液器电容补偿只需按下按钮即可抵消玻璃移液器和移液器支架对电路电容的影响。
串联电阻补偿：通过瞬时增压膜电位，预测有助于更快地达到所需的指令水平。
串联电阻补偿：校正通过消除串联电阻上的压降引入的误差来提高记录带宽。
通过单击鼠标，自动细胞电容补偿可校正全细胞记录中细胞膜的电容。
自动模式切换使您能够通过外部触发器或根据记录的信号来控制电压和电流钳位之间的转换。
发生电反馈时，自动振荡检测可防止对电池造成损坏。
使用基于软件的智能算法自动校正泄漏电流的泄漏减法。
具有 11 种设置的可选输出增益，可将输出信号缩放到所需水平。
当您忙于俯视显微镜时，音频监视器可对信号进行声学跟踪。
可微调的 4 极贝塞尔和巴特沃斯低通滤波器用作抗混叠滤波器，可用于对输出信号进行预处理。

主要附件及配置

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