主要规格及技术指标

1. 检测原理：表面等离子体共振
2. 每循环时间：2-15 分钟；
3. 进样体积：2–350 μl
4. 流速：1–100 μl/min；
5. 数据采集频率1 or 10 Hz
6. 分析温度范围：4–45°C；
7. 折射系数范围：1.33–1.40；
8. 响应信号动态范围：1-70000 RU；
9. 缓冲液选择器：在四种溶液间自动转换。

1. Detection principle: Surface plasmon resonance
​​2. Cycle time:​​ 2–15 minutes;
3. ​​Injection volume:​​ 2–350 μl;
4. Flow rate:​​ 1–100 μl/min;
​​5. Data acquisition frequency:​​ 1 or 10 Hz; ​​
6. Analysis temperature range:​​ 4–45 °C;
​​7. Refractive index range:​​ 1.33–1.40;
8. ​​Response signal dynamic range:​​ 1–70,000 RU;
9. Buffer selector:​​ Automatically switches between four solutions.

主要功能及特色

1. 高灵敏度与宽动态范围：既能检测小分子药物，也能分析抗体等大分子生物制剂；浓度覆盖范围宽，无需对样品进行繁琐稀释。
2. 实时无标记分析：无需荧光、放射性等标记物，直接实时监测分子结合、解离的完整动力学过程，可直接获取kon（结合速率常数）、koff（解离速率常数）、KD（亲和力常数）等核心数据。
3. 高通量与自动化：4通道并行检测搭配384孔自动进样器。
4. 全流程多功能分析模式：覆盖药物研发等场景的全流程需求，包括动力学分析、亲和力测定、浓度定量、特异性/竞争性结合分析，以及热力学分析。
5. 高稳定性与重复性：依托精准的±0.1°C温控和优化的芯片设计，确保结果稳定可靠。

1. High sensitivity and wide dynamic range: It can not only detect small molecule drugs but also analyze large molecule biological agents such as antibodies. The concentration coverage is wide, and there is no need for cumbersome dilution of the sample.
2. Real-time label-free analysis: Without the need for fluorescent, radioactive or other markers, it can directly and in real time monitor the complete kinetic process of molecular binding and dissociation and directly obtain core data such as kon (binding rate constant), koff (dissociation rate constant), and KD (affinity constant).
3. High throughput and automation: 4-channel parallel detection combined with a 384-well autosampler.
4. Full-process multi-functional analysis mode: Covering the full-process requirements of scenarios such as drug development, including kinetic analysis, affinity determination, concentration quantification, specific/competitive binding analysis, and thermodynamic analysis.
5. High stability and repeatability: Relying on precise ±0.1°C temperature control and optimized chip design, the results are ensured to be stable and reliable.

主要附件及配置

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