Requirements for Preparative Infusion Pump
1.1 Operating Mode: It shall constitute a binary high-pressure gradient system with independent infusion pumps.
1.2 It shall adopt a floating structure to support the plunger device, eliminating the need for a damper transmission mechanism.
1.3 Flow Rate Range: 0.001-20.0000 ml/min.
1.4 Flow Rate Precision: 0.1% RSD (Relative Standard Deviation).
1.5 Flow Rate Accuracy: ±1%.
1.6 Maximum Discharge Pressure: 49 MPa at flow rates of 0.01~20 ml/min.
1.7 Gradient Composition Range: 0.0-100.0%, with 0.1% increments.
1.8 Gradient Mixing Accuracy: ±0.5%, unaffected by back pressure.
1.9 Gradient Composition Precision: Within 0.1% RSD.
Detection Section: Utilize a UV detector to obtain UV signals.
2.1 UV Detector
2.1.1 Light Source: Deuterium lamp.
2.1.2 Wavelength Range: 190~700 nm.
2.1.3 Dual-Wavelength Function: Supported.
2.1.4 Drift: <0.1×10⁻³ AU/h.
2.1.5 Noise: <5.0×10⁻⁶ AU.
2.1.6 Linear Range: >2.5 AU.
2.1.7 Temperature Coefficient: <0.3×10⁻³ AU/℃ (at 250 nm, methanol 1 ml/min).
2.1.8 Standard Cell: Optical path: 10 mm, cell volume: 12 μL, pressure resistance: 12 MPa.
2.1.9 Flow Cell ID/Light Source ID Function: Identify the IDs of the flow cell and light source, and record them in data files and system inspection reports.
2.1.9.1 Flow Cell Temperature Control: Adjustable.
2.1.9.2 Temperature Control Unit: Standard configuration includes the optical system and flow cell.
2.1.9.3 Flow Cell Temperature Control Range: 9~50℃, with 1℃ increments.
It is primarily utilized for the separation, analysis, and preparation of target compounds and impurities in pharmaceuticals, natural products, organic synthesis, and other fields. By automatically slicing and distinguishing chromatographic peaks, it enables chromatographic analysis and detection of purified compounds. The entire process is fully software-controlled, eliminating the need for manual switching. Additionally, the integrated online system for trapping, concentrating, purifying, and recovering substances can effectively remove modifiers from the mobile phase, thereby enhancing product purity and recovery rates.
LC-20AR Solvent delivery unit;
SPD-20A UV-VIS Detector;
FRC-10A Fraction Collector;
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