主要规格及技术指标

I. Core Performance:
1. Ultimate vacuum: –0.085 MPa—sufficient to generate the vacuum required for microneedle filling, effectively eliminating bubbles in high-viscosity hydrogel formulations.
2. Power rating: 20 W—low consumption for energy-efficient, bench-top operation in research labs.
II. Key Component Specs:
1. Connection tube: 8 mm O.D., links the vacuum pump to the filling-tank valve, ensuring a sealed, stable vacuum line.
2. Accessories: supplied with a dedicated filling-tank kit, 3 valves, 10 stoppers and 5 filling needles—covering routine use and spare-part needs.
III. General Specs:
1. Net weight: 1.8 kg—lightweight and easy to move or store on crowded lab benches.
2. Standard package: 1 vacuum pump, 1 connection tube, 1 roll of PTFE sealing tape and a complete microneedle accessory set—ready for immediate assembly and use straight out of the box.

一、核心性能指标：
1、极限真空度：可达-0.085MPa，该性能可满足微针制备时注液环节的真空环境需求，助力解决水凝胶等微针材料注液时的气泡问题。
2、设备功率：为 20W，功率较低，在科研实验室等场景使用时更节能环保，适配小型实验环境的用电需求。
二、关键部件规格：
1、连接管：外径规格为 8mm，用于连接真空泵与注液罐的连接阀，保障真空通路的密封性和稳定性。
2、配套配件规格：搭配专用注液罐套件，同时附带3个连接阀、10个进样塞以及5个进样针，可满足日常实验的基础使用和损耗替换需求。
三、其他基础规格：
1、设备净重：仅1.8kg，重量轻，便于在实验室桌面移动和收纳，适配小型科研实验台的摆放场景。
2、组成配置：整机标配1台真空泵、1根连接管、1个备用生料带，以及1套完整的微针方案配件，开箱后可通过简单组装投入使用。

主要功能及特色

Hydrogel-based microneedles versus conventional metal or silicon needles offer decisive advantages:
1. High drug loading plus on-demand, zero-order release profiles.
2. Matrix made from biomedical-grade polymers—biocompatible and unlikely to leave splinters that could damage skin.
3. Cross-linked hydrogels swell subcutaneously but do not dissolve, sustaining drug release for longer periods.

Yet fabricating hydrogel microneedles is fraught with challenges: high-viscosity solutions that trap air, needle shrinkage, uneven substrates, irregular tip geometry and poor tip strength. To streamline production, EFL has packaged a complete “microneedle toolbox” covering four critical steps—material selection, mold matching, tip filling and drying/release.
1. Material selection:
EFL supplies both photocurable and non-photocurable biomedical polymers optimized for microneedle processing.
2. Mold matching:
Drawing on long-term customer feedback, EFL has refined the most frequently requested microneedle mold geometries.
3. Tip filling:
3.1. Option1: Vacuum degassing (EFL-VDM-001 vacuum chamber);
3.2. Option2: Vacuum-assisted liquid filling with the EFL-VLF100 microneedle filling station.
4. Drying & demolding:
Drying conditions dictate final tip shape, drug stability and patch flatness. EFL’s Microneedle Drying Kit (EFL-VLF-006) isolates patches from ambient airflow and humidity, enabling controlled drying at low, room or elevated temperature to yield uniform, defect-free microneedle arrays.

基于水凝胶等生物材料的微针相比传统金属、硅基微针具有以下显著优势：
1、具有载药量大和可控的药物控释效果。
2、针体材料由高分子生物材料构成，生物相容性良好，避免针尖断裂对皮肤造成的潜在损伤。
3、采用交联的高分子生物材料制备微针可实现微针在皮下溶胀而不溶解，进而使药物释放更持久。

然而，水凝胶基微针的制备也面临多重挑战。例如：溶液黏度高，注液除泡难度大、微针易皱缩、衬底不平整、针形不规整、针尖强度低等。为了解决上述问题，让微针制备更高效，EFL总结并推出微针制备整套解决方案，涉及如下关键环节：材料选择、模具适配、针尖填充、干燥脱模。
1、材料选择：
EFL提供用于制备微针的光固化生物材料和非光固化生物材料。
2、模具适配：
根据EFL技术支持团队与用户的长期沟通反馈，EFL团队优化了常用规格的微针模具。
3、针尖填充：
3.1、方案一:真空除泡工艺（适配真空除泡装置EFL-VDM-001）；
3.2、方案二:真空注液工艺（适配微针注液装置EFL-VLF100）。
4、干燥脱模：
微针干燥过程对其形貌及性能有很大影响，条件控制不当可能造成针尖形变、衬底与针尖分离、衬底空壳、衬底皱缩不平、药物失活等问题。EFL基于长期工艺研究经验推出适配不同工艺条件的微针干燥套装(EFL-VLF-006），该套装不受外界气流和湿度干扰，可在低温、室温及高温条件下完成微针干燥，获得规整微针贴片。

主要附件及配置

无