主要规格及技术指标

质量分析系统
质量范围：m/z 20–60,000（适用于生物大分子与小分子分析）
分辨率：> 40,000 FWHM（在m/z 1,922处，全质量范围内保持高分辨率）
质量准确度：< 1 ppm RMS（外标法）；< 0.5 ppm RMS（内标法）
扫描速度：最高20 Hz（全质量范围采集，适用于UHPLC联用）
离子源与电离方式
电离源：电喷雾电离（ESI），支持正/负离子模式
离子传输效率：优化的离子光学设计，减少信号损失
兼容性：可选配纳升电喷雾（nano-ESI）、大气压化学电离（APCI）等接口
四级杆与碰撞室
四级杆质量过滤器：质量选择范围m/z 50–3,000
碰撞诱导解离（CID）：多级能量可调（MS/MS功能），支持靶向碎裂
检测系统
检测器：高动态范围混合型ADC检测器（40 GHz采样率）
灵敏度：
全扫描模式：1 fmol 利血平（S/N > 200:1）
MS/MS模式：10 amol 血管紧张素I（S/N > 50:1）
真空系统
真空泵配置：分子涡轮泵与机械泵组合，维持<10⁻⁷ mbar的高真空
启动时间：< 3小时达到工作真空
软件与数据处理
控制软件：Bruker Compass HyStar 和 DataAnalysis
功能：自动调谐、实时谱图解析、分子式预测、代谢物筛查
Mass Analysis System
Mass Range: m/z 20–60,000 (suitable for both biomacromolecules and small molecules)
Resolution: > 40,000 FWHM (at m/z 1,922, maintained across the full mass range)
Mass Accuracy:
< 1 ppm RMS (external calibration)
< 0.5 ppm RMS (internal calibration)
Scan Speed: Up to 20 Hz (full mass range acquisition, compatible with UHPLC coupling)
Ion Source and Ionization
Ionization Source: Electrospray Ionization (ESI), supporting positive/negative ion modes
Ion Transmission Efficiency: Optimized ion optics design minimizes signal loss
Compatibility: Optional interfaces include nano-electrospray (nano-ESI) and atmospheric pressure chemical ionization (APCI)
Quadrupole and Collision Cell
Quadrupole Mass Filter: Mass selection range m/z 50–3,000
Collision-Induced Dissociation (CID): Adjustable multi-stage energy (MS/MS capability), enabling targeted fragmentation
Detection System
Detector: High dynamic range hybrid ADC detector (40 GHz sampling rate)
Sensitivity:
Full scan mode: 1 fmol reserpine (S/N > 200:1)
MS/MS mode: 10 amol angiotensin I (S/N > 50:1)
Vacuum System
Vacuum Configuration: Combination of molecular turbo pump and mechanical pump, maintaining ultra-high vacuum (<10⁻⁷ mbar)
Startup Time: < 3 hours to reach operational vacuum
Software and Data Processing
Control Software: Bruker Compass HyStar and DataAnalysis
Features:
Automatic tuning
Real-time spectral interpretation
Molecular formula prediction
Metabolite screening
This translation retains technical accuracy while adhering to standard scientific terminology in English. Let me know if further adjustments are needed!

主要功能及特色

On the basis of the excellent performance of the micrOTOF series mass spectrometer, the resolution of the micrOTOF-Q II mass spectrometer is even as high as 20,000 FWHM, and it also has excellent mass accuracy for fragment ions and a flexible MS/MS automatic acquisition strategy based on data results. Therefore, the application field of micrOTOF-Q II has been further expanded to de novo sequencing of unknown peptides, including high-confidence identification of post-translational modifications. In addition to proteomics, micrOTOF-Q II also has high-confidence results for the structural analysis of small molecule compounds.
Excellent high quality accuracy, high resolution resolution and true isotope peak shape (TIP) determination, the perfect combination of these three makes micrOTOF-Q II a true molecular formula generator. The true isotope peak shape determination of precursor ions and fragment ions is an important feature of the molecular formula generated by mass spectrometry.
在micrOTOF 系列质谱卓越性能的基础上，micrOTOF-Q II 质谱的分辨率甚至高达20,000 FWHM，并且对碎片离子也具有优异的质量准确度以及灵活的基于数据结果的MS/MS自动采集策略。因而，micrOTOF-Q II 的应用领域进一步拓展到未知肽段从头序列测定（de novo sequencing），包括翻译后修饰高可信度的鉴定。除了蛋白质组学，micrOTOF-Q II 对小分子化合物的结构分析同样具有高可信度的结果。
卓越的高质量准确度、高分辨分辨率和真实同位素峰形（TIP）测定，这三者的完美结合使得micrOTOF-Q II 成为真正的分子式生成器。母离子和碎片离子的真实同位素峰形测定，是质谱测定产生分子式的重要特征。

主要附件及配置

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